مقالات  صدیقه کشاورز  


  The effect of antidepressant treatment on the HPA axis, changes in depression score and serum levels of TNF-α in depressed infertile women Revista de Psiquiatria Clínica:Archives of Clinical Psychiatry February 2020:47(1):7-12 ISI, Scopus, Embase, DOAJ SEDIGHEH KESHAVARZ,BAHAR MORSHED-BEHBAHANI,MOHAMMAD EBRAHIM PARSANEZHAD,AHMAD GHANIZADEH,MEHRAP SAYADI,MARZIEH AKBARZADEH اول
ABSTRACT Objectives This study aimed to explore the effect of antidepressant treatment on the HPA axis, changes in depression score, and serum levels of TNF-α in depressed infertile women. Methods In this randomized controlled trial research, 60 infertile women who had undergone in vitro fertilization (IVF) treatment with depression scores between 16-47 were divided into two groups. The intervention group with fluoxetine capsule was under treatment for two months before the embryo transfer, while the control group was given placebo. Depression score, serum levels of tumor necrosis factor alpha (TNF-α) as well as cortisol hormone levels were measured and recorded both before and after the intervention. The data were analyzed using SPSS version 21 software. Results We analyzed the data related to 55 subjects who had undergone embryo transfer. 7 subjects in the intervention group and 3 in the control group got pregnant. We observed a significant decrease in the depression score (p < 0/001) and serum levels of cortisol (p = 0/001) in the intervention group. There was a significant increase in the serum levels of TNF-α in the intervention group (p < 0/001). There was a significant difference between the two groups in the number of pregnancies (p = 0.04). However, there was no statistical difference between them with regard to the number of harvested oocytes (p = 0.174). Discussion Decrease in depression score and cortisol level, and an increase in the levels of TNF-α in the intervention group caused any changes in the number of oocytes in comparison with the control group. However, the number of pregnancies was larger in the intervention group. Key words: TNF-α; infertility; depression; HPA axis; treatment

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https://www.scielo.br/scielo.php?pid=S0101-60832020000100007&script=sci_arttext

  Comparison of midwifery consultation and fluoxetine on IVF outcomes in depressed infertile woman: a clinical trial research study Current Women`s Health Reviews August 2020 ISI, Scopus, Embase Sedigheh Keshavarz, Bahar Morshed-Behbahani, Mohammad Ebrahim Parsanezhad,Marzieh Akbarzadeh اول
Abstract: Background: A lot of research has been done to improve the treatment of infertility and increase the quality and effectiveness of performance. Objective: In this randomized clinical trial study (IRCT2014031116911N2), we compared the effect of Fluoxetine and midwifery consultation on infertile women suffering from depression and the focus of the study is on the results of, InVitro Fertilization (IVF) treatment. Methods: 90 infertile women who suffered from mild to moderate depression according to Beck Inventory and had undergone IVF treatment were selected and randomly divided into 3 groups. The control group, the second group were treated with Fluoxetine 20 mg, and the third group received 6 sessions of midwifery consultation and then the outcomes were reviewed. The amount of cortisol in the women’s sera was measured in three stages and the level of depression and anxiety was measured in two stages. Results: Pregnancy rate in the midwifery consultation group (n=13) was about two times as high as that in the fluoxetine group (n=7) and three times as high as that in the control group (n=4); there was a statistically significant difference among the groups (P=0.016). As to the abortions occurring in each group (P>0.05). Conclusion: Providing the people undergoing IVF treatment with emotional and mental support will increase their chances of pregnancy and this kind of support will be helpful for the patients if it is given in the form of midwifery consultation. Keywords: Infertility, depression, Fluoxetine, midwifery, consultation, IVF

https://www.eurekaselect.com/185338/article

  Certain prenatal problems and their relationship with neonate's anthropometric indices at birth International Journal of Pediatrics August 2020 ISI Sedigheh Keshavarz ,Maryam Chananeh , Khatoon Samsami ,Nadieh Pakari,Razieh Bagherzadeh اول
Abstract Background and Objective: Fetal development is a strong predictor of neonate's survival after birth. Investigation of factors that may affect fetal development is important. The present study aimed to investigate certain prenatal problems and their relationship with neonate's anthropometric indices at birth. Materials and Methods: The present cross-sectional descriptive-analytical study was conducted using records registered in Iran’s Integrated Health System (locally know as SIB), including the records of 616 pregnant mothers who had given birth during 2017-18 in the city of Bushehr (Iran). The registered details of the mothers and infants were reviewed from the first prenatal visit to the first postpartum visit. A checklist was prepared to record the information in their records. The collected data were analyzed in SPSS-19 using appropriate statistical tests at a significance level of p<0.05. Results: The mothers' mean age was 30.84±5.30 years, 3.9% of infants weighed under 2500 g and were therefore in LBW group. The frequency of anemia was 16.25% and 22.5% respectively in the first and second trimesters. Gestational age (β=0.157, P<0.001), multiparity (β=0.112, P=0.005) and the infant's male gender (β=0.117, P=0.004) had a direct and significant relationship, and vaginal childbirth an inverse and significant relationship (β=-0.122, P=0.003) with the infant's head circumference. Gestational age at birth (β=0.195, P>0.001) and mothers’ body mass Index (BMI) (β=0.241, P>0.001) in the first prenatal visit had a direct and significant relationship with the infant's weight-for-age Z-score. Moreover, GA (β=0.229, P>0.001) and mother's BMI (β=0.242, P>0.001) in the first prenatal visit had a direct and significant relationship with the infant's length-for-age Z-score. The infant's anthropometric indices had no significant relationships with perinatal complications such as anemia, controlled diabetes, and urinary tract infections. Conclusion: Prenatal complications such as anemia were prevalent in the study population, and required particular attention. The mother's BMI can predict fetal development and should be the focus of greater attention in prenatal clinics. Closer monitoring of maternal anthropometry and increasing mother's knowledge in nutrition by the antenatal clinics would be beneficial for both the mother and the neonate. Keywords Birth Weight Low Birth Weight Neonate Perinatal Care

https://ijp.mums.ac.ir/article_16320.html

  Why Iranian Women Experience Work-Family Conflict? Current Women`s Health Reviews September 2020 ISI, Scopus, Embase Ziba Taghizadeh,Abbas Ebadi,Sedigheh Keshavarz,Abolghasem Pourreza,Razieh Bagherzadeh* سوم
Abstract: Background: Despite the global importance of work-family issues and the many calls for studies within distinct cultural contexts; work-family research has mainly been conducted in Anglo societies, and Western countries. Objective: The present study was designed to explore the factors which determine work-family conflict through personal information including, but not limited to the lived experiences and perspectives of Iranian women who are both employed and married. Methods: A qualitative approach was chosen which would allow for an in-depth and rich exploration of the experiences, perceptions, and feelings of participants. Data were obtained from 29 participants. In-depth individual interviews with 17 participants and two focus groups. Each focus group discussion included 6 participants. Results: Six main categories emerged from the data analysis: the value of work and family, hegemonic masculinity, nonsupportive environment, job stress, overloading family, and inadequacy of individual ability and skills. Conclusion: Based on data obtained from participants, sociocultural factors play an important role in the creation of work-family conflict. Keywords: Work-family, Conflict, Women, Qualitative study, Iran, Iranian Women

https://www.eurekaselect.com/186058/article

  The relationship between the type of nutrition and anthropometric indices of infants during the first year of birth International Journal of Pediatrics September 2020 ISI Maryam Chananeh,Nadieh Pakari,Sedigheh Keshavarz,Khatoon SamsamiRazieh Bagherzadeh سوم
Abstract Background: Considering the importance of proper infant nutrition, especially in the first two years of life, and also the effect of cultural subjects on the type of infant's nutrition, this study aimed to investigate the type of nutrition and anthropometric indices of infants during the first year of birth in Bushehr, Iran. Methods and materials: This cross-sectional study carried out on 546 delivered mothers. The data of mothers and their children were collected through Integrated Health System (SIB). Five centers of comprehensive health care centers were randomly selected. Required information included maternal demographic characteristics and anthropometric indices of infants at birth, 6 and 12 months. The collected data were analyzed using SPSS 19 with appropriate statistical tests at a significance level of p Results: The frequency of exclusive breastfeeding, formula feeding and also both feeding methods (combined) were 56.8%, 25.1%, and 18.1%, respectively. The results showed that 6-month weight gain compared to birth time did not differ between the three groups. The increase in height and head circumference in the first six months in the formula feeding group was less than the exclusive breastfeeding group and the combined group (p <0.05). In the second six months, weight gain and height in formula feeding group were less than the other two groups (P <0.01). Conclusion: This study showed that the prevalence of exclusive breastfeeding in Bushehr is desirable with good condition compared to the whole country of Iran. The growth trend in breastfed infants is either similar or better than formula-fed infants. Use of formula with breast milk compared to formula alone has better growth outcomes. Keywords Exclusive breastfeeding formula feeding breastfeeding

https://ijp.mums.ac.ir/article_16736.html

  A Comparative Study of the Influence of Midwifery Consultation on the Knowledge and Attitude of Infertile Women with Mild to Moderate Depression Undergoing IVF Journal of Medical Sciences January 2017: 5(7):2775-2780 Sedigheh Keshavarz,Marzieh Akbarzadeh,Bahar Morshed behbahani,Najaf Zare اول
Abstract: The aim is to investigate that how much midwives' consultation can influence depressed infertile women's attitude and knowledge, to improve their quality of life and their probable success in their treatment. In this study sixty mild to moderate (scared 10-47) depressed infertile women were chosen by easy purposive sampling by Beck Depression Inventory (BDI). Patients in midwifery consultation group were consulted and guided in three fields and six sessions, consultation and advice for patients was from 8 weeks before embryo transfer until the transfer day. The level of the knowledge and attitude of consulting group after consultation sessions has increased dramatically and significant (p<0.001). But in control group no significance is seen. From the finding of these studies it can be concluded that consultation by the people who have hands on professional infertility treatments and also know consultation techniques and support of infertile people can improve these people's knowledge and their change of attitude. Keywords: midwifery consultation, infertility treatments, Beck Depression Inventory (BDI).

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  The Relationship between Changes in Serum Cortisol levels and IVF Results in Infertile Women with Mild to Moderate Depression SAS Journal December 2015: 1(4):144-148 Bahar Morshed behbahani,Marzieh Akbarzadeh,Mohammad Ebrahim ParsanezhadShow all 7 authorsMina Jamshidi,Najaf Zare,Ahmad Ghanizadeh,Sedigheh Keshavarz,Mina Jamshidi
Abstract: The purpose of the study was to investigate the relationship between the cortisol hormone levels of depressed infertile women with their IVF results throughout the treatment process to identify the consequences of IVF. In this prospective study, 74 women who were being treated by IVF at the Mother and Child Infertility Center of Shiraz and were affected by mild to moderate depression based on Beck inventory were randomly selected as the subjects. The sampling and follow-up were performed from April 2014 to March 2015. Cortisol levels were measured in the patients' serum at three stages: 1) before the treatment (T1), 2) on the day of egg retrieval (T2), and 3) and on the day of transferring the embryo to the uterus (T3). Sampling was conducted from 9 a.m. to 10 a.m. To analyze the data, the researchers used SPSS. In findings 32.43% of the subjects got pregnant after the treatment, and 54.16% miscarried before the eighth week of their pregnancy. The researchers did not find a significant relationship between the subjects' depression scores and pregnancy outcome. In patients with a low cortisol level on the day of egg retrieval, chances of pregnancy were significantly higher (p=0.01). The relationship between the two variables of imperfect eggs and cortisol level was significant (p=0.011); higher levels of cortisol at the beginning of treatment correlated with a greater number of imperfect eggs in patients. The relationship between the number of miscarriages and cortisol levels was not significant. In conclusion, there is a significant relationship between the level of the hormone cortisol in the serum of patients undergoing IVF and their pregnancy and number of imperfect oocytes. Therefore, controlling anxiety and depression in infertile women, which results in lower levels of cortisol during their IVF treatment, can lead to better treatment outcomes. Keywords: Cortisol, IVF, infertility

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